Biggest problem i have is all the Mod tools are Windows based and i have not had much luck getting WINE to handle them
gosh Audio editor , things are getting complicated , is there a idiot proof, free program somewhere, save me looking?
"Since the programs are .NET-based, have you tried using Mono instead?" What is Mono?
I think slightly better mic and/or audiocard will do this job much better than any audio editor. Cleaning noise after recording is not very good idea, since there still will be some (and quite a lot, if my hear it right) audible artifacts.
Audacity [...] only works with audio files though, so you would have to record your mic and screen separately and combine them afterwards. I can post my video process later if you think it'll help.