In my current campaign, I have once again been plagued by bad RNG. It took a very long time to have a chance to get navigator. I did not have any artifact site missions with the sharkmen (which would have enabled me to obtain a live Oct terrorist, which would unlock advanced MC before the freaks come and made certain other missions much easier), and now (Jan 2039) capturing a live Oct is not even possible anymore, unless I chance upon and shoot down a sharkmen battleship going on a terror mission. So likely I should do the alien dungeon first so that freaks start to appear. I also have had only one terror mission with bio-drones, which I had no other option than to abort (I guess I should have forced through to capture at least one even with heavy losses). The only other way to get bio-drone is through enhanced aquatoid/freak medic and there is no alternative path to Oct terrorist. The furthest weirdness has been that I have yet to see a single Naga temple mission, which has 50% of chance to occur after Naga society (temples are an easy mid-game way to churn a few alien implanters, for example, not that I have a dire need anymore).
EDIT: apparently you can't get sonic weapons manufacturing through those medics either, I misunderstood the dependencies.
I suppose the game is offering me a chance to try a run without offensive MC but I'm not overly enthusiastic, given that in particular psiVision with MC armor is so exceptionally powerful a tool in missions consisting of multiple levels (e.g. base attacks, jellymen tsunamis, biolabs, barges, ...).