My typical loadout for intercepting bigger ships (which I admittedly don't do very often at all) is a Kraken or Dragon to tank, with the biggest heavy weapons I have, 2 barracudas with 4x Tesla cannons, and 1 more ship outfitted with the most damage potential I have available, like a dragon with 4x plasma beams, a saber with 2x laser cannons and 2x Meteor missles, etc. Honestly though I hardly ever do ship interceptions unless I have to, like that stupid secure freight or bombers for the tech gates, or the science vessel for the scientist (unless I already got one from campus carnage). Most ships will land somewhere so I have my transport tail anything that will land and not worry about the other stuff unless I have to as mentioned before.