How am I doing:
Just got through the first year. I have two bases (one is an outpost/storage facility). My first power station is about to be completed. Ive got chainmail for most of my hands, researched the tiny drill and got the gray codex with it. Still cant really make any guns, but oddly I can make ammunition for some of them (none of the ones I want to make ammo for really though)
Consistently had 10 Brainers and 30 Runts for most of the year, added Runts up to 50 after the workshop (completed in Sept I think) was built, though I added an Extractor to increase the number of runts prior to that. I could have built another workshop but it just costs too much.
I Make a good deal of money on Chateau De La Mort from the apples collected in the ratmen maps. When that runs out I make X-Grog.
Ive got an aircar thats still using the charger laser I started the game with. I had a turtle and sold it (I bought and sold it when it was ~650 in the previous version, now that its 1.1 mil I wont be buying it again), I can usually do what I need to do with 4 ladies anyway. Only other weapon bearing crafts available are the shark jetbike and the airspeeder. Other than the conversion launcher I got from the gray drill I havent been able to make any other craft weapons, and the seagull launcher/missiles are too pricey to use.
Havent shot down any ships that shoot back yet, only civilian traffic, might have shot down one that fired a few times and missed.
Ive engaged in 2 pogroms, usually crap score, near zero or negative, mutants end up almost completely dead but at least my hands make it out alive (mostly). I completely skipped the one with the doom monsters, I only killed three monsters despite all my efforts so I just reloaded a prior save and let it be. I didnt research Mutant Alliance until about Oct because I had the notion it would force going to pogroms or lose points.
Ive got over 2000 chips combined of the $200 and $1000 variety because the research said it was possible to hack them up to Silver level (5000) but when I took a peek at the research rules it looks like its gonna be a loooong time before that can be done.
Ive continously skipped about 8 or 9 undersea adventures because I have no underwater weapons, and there are man-sharks that kill me instantly. I got undersea adventure sometime early on like march. So I might go there just to look at the scenery but I dont do anything. I can get oxygen tanks but without weapons its not worth it, wherever the treasure is on the map I usually cant find it and there's usually critters guarding it. (whatever ruleset/scripting is used to remove the normal items sounds like a good way to make Land Only use items for TFTD as well, might take notes to deprive soldiers of grenades in tftd).
It seems my most effective weapons right now are Cattle Prods, Harpoon Guns (with stun darts), Boom Fruits, and ive used the Military Shotgun with AP shells to decent effect in the Pogroms. Also the Clockwork Musket pistol, that thing does outrageous damage but its balanced for being unwieldy.
Also most of my ladies are stellar with melee attack and strong as hell, the Saber/Axe/Billhook are able to kill some enemies that guns barely scratch (like the "humongous raider").
Year End: ive got about $6,100,000
Edit: Will also say that the animal hunts generally kill me so I avoid those. I can take down the white shambler no problem now, and I can manage to put down bloodhounds and megascorpions, but I avoid chupacabras like they're chrissys (I just cant kill them, and they make short work of my ladies). As it stands I only kill a few bloodhounds/scorpions and I drag the carcasses back into the ship.