Riot grenades are really great for taking out tougher enemies that you'd like to take out non-lethally, if possible. I usually use hallucinogen/knockout gas, but stronger enemies are often immune to choking damage. Also, IIRC, harpoon tranquilizers are 75 daze while Riot grenades are 72, against under armor however. In particular I've taken out some Marsec Colonial Marines(The guys in red armor with red shields in viper fighters) which were impervious to most of my other weaponry. In general trying riot grenades against tougher enemies that you'd like to take non-lethally has never been a bad idea for me.