The random spawning of aliens on (any) terrain leads sometimes to extreme numbers of units in one building. Had a small farm building in my last mission (10x10) and it contained no less than 6(!) sectoids, and a 7th one was running out of it/at the door of it before i leveled the whole thing with rockets.
I like the randomness, but I do not know if this is actually how it is supposed to be...
It would also explain the high number of civilians in one location that some Piratez-Mod users reported.