Thanks for the tips! I discovered the middle click for techs by accident, it's been a big help. I was misled for a while by it though, on interrogations and autopsies I thought I had to have a biolab at first, which slowed me down quite a bit. Once I realized I could do autopsies and stuff without a biolab I did somewhat better.
So far I am doing OK on most missions except chupacabras and spider infestations. Chupacabras = instant abort, there is nothing fun about having your four person squad wiped out by super-fast, super-damaging uber-monsters. Honestly, I am not sure why they are showing up so early unless they are put there to deliberately wipe out your squad. I only have Kevlar vests and regular guns, so I have zero chance against them. That is the one mission I allow myself to reload because it's too ridiculous.
The first half of the spider mission is OK, but I literally can't carry enough ammo and stuff for the second part. Also the combination of color scheme and darkness in the caves make it almost impossible for me to see anything, especially since spiders are tough to spot in the first place. I usually do the first half of these missions then abort on the second half so my score isn't quite so awful.
Right now I am finding a combination of HKs, Magnums, Shotguns, and Tasers to be the most effective loadouts for my 4 person squads, along with medikits and heal sprays. I take every mission I can, but sometimes I can't reach a mission in the van before its timer expires and there is no way I am sending a two person team anywhere anymore. I really hope I get decent transport soon!
I have started interrogating gang members and raided a Cult of Dagon safe house. I am really looking forward to the various story arcs!