Long story short, I recently read some sci-fi (WH40K sci-fi, don't hate me) and one of the more interesting encounters in the book was a shootout at a circus.
The circus in the book was much more like the Roman Coliseum than Ringling Bros. Gladiators fought each other, mutants were forced to fight large wild animals, large wild animals fought each other and so on, with acrobats, clowns and popcorn.
This might make an interesting mission-type for the game. Maybe the gals have to rescue some ubers/mutants, maybe they are just there to steal the takings. Whatever their reason, they would have to fight their way through gladiators, clowns, animal handlers, the animals themselves, clowns, the hunters that bring in the animals, clowns, popcorn vendors and clowns.