Leaving this here (hopefully in the correct place) to help someone who may have run into a similar situation as I have.
Cyberweb Lair missionsMaybe a tips menu added to the intro screen or something.
In order to complete this mission i had to use
High explosives to blow through walls in order to gain access to entries where enemies were hiding.
And this was no easy task, it took a lot of save scumming because you need to use explosives (or very high powered ammo to blow through walls at a specific point.
Most of the walls were 2 tiles thick, but precise placement of explosives would reveal an entrance door.
This is similar to something I saw in TFTD. In the final mission, one alien was hiding inside a wall.